Department of Biological Sciences Seminar
October 18th, 2013; 2:30 pm
In search of biomarkers in cells of patients with autism spectrum disorders (ASDs)
Chin-Fu Chen, Ph.D.
Assistant Research Scientist
Center for Molecular Studies and
Office of Bioinformatics and Epidemiology
Greenwood Genetic Center
Autism spectrum disorders (ASDs) refer to a group of developmental brain disorders with different levels of impairments in social, communication, and behavioral functions. The diagnosis of ASDs is based upon behavioral or developmental observations and no laboratory tests are available. With more than 1% of children affected by ASDs each year in the US, the need for an objective, reliable laboratory test is paramount. Using Biolog Phenotype MicroArrays, we have collected data of the metabolic profile of lymphoblastoid cell lines, as well as lymphocytes from fresh blood, from patients with neuro-developmental disorders with or without ASDs and normal individuals. This talk will illustrate the application of statistical and machine learning methods for identification of possible biomarkers in cells of ASD patients.
As usual, all seminars in our series are free and open to any interested public. Please visit our seminar calendar for more information and other events.
Dr. Charlie Wei
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